Age of Infection with Kaposi Sarcoma-Associated Herpesvirus and Subsequent Antibody Values Among Children in Uganda.
Angela
Nalwoga
;
Wendell
Miley
;
Nazzarena
Labo
;
Alison
Elliott
;
Stephen
Cose
;
Denise
Whitby
;
Robert
Newton
;
(2018)
Age of Infection with Kaposi Sarcoma-Associated Herpesvirus and Subsequent Antibody Values Among Children in Uganda.
The Pediatric infectious disease journal, 37 (8).
e225-e228.
ISSN 0891-3668
DOI: 10.1097/INF.0000000000001909
;
Wendell
Miley
;
Nazzarena
Labo
;
Alison
Elliott
;
Stephen
Cose
;
Denise
Whitby
;
Robert
Newton
;
(2018)
Age of Infection with Kaposi Sarcoma-Associated Herpesvirus and Subsequent Antibody Values Among Children in Uganda.
The Pediatric infectious disease journal, 37 (8).
e225-e228.
ISSN 0891-3668
DOI: 10.1097/INF.0000000000001909
We investigated associations between Kaposi sarcoma-associated herpesvirus (KSHV) seroconversion age and KSHV antibody values in Ugandan children. Every annual delay in KSHV seroconversion age was associated with a reduction of 19% (P < 0.0001) in K8.1 and 27% (P < 0.0001) in ORF73 antibody values at 6 years of age. Early infection may be an important risk factor for KSHV pathogenesis and viral shedding in saliva, leading to transmission.
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